Medicinal properties of Hibiscus

On January 28, 2011 in General

Lotrisone For Sale Propecia Generic Buy Inderal Online Amoxil Without Prescription Prevacid No Prescription Zyban For Sale Clarinex Generic Buy Zyban Online Lipitor Without Prescription Neurontin No Prescription

There is an increasing demand for the herbal drug treatment for various ailments. Many plant drugs from traditional medicine like Ayurveda are being explored globally. One of  the most common plant we came across to our day to day life is China rose or shoe flower.It’s botanical name is Hibiscus and belongs to family Malvaceae.Malvaceae is quite big family and has about 200to220 species.Hibiscus is native to tropical Asia and the plant is commonly found throughout the tropics and as a house plant throughout the world.The medicinal uses of Hibiscus were known from a long time ago. Hibiscus has a major diuretic effect[1], Hibiscus rosa sinensis Linne is effective against diabetes[2] and wound healing activity[3] [4].Hibiscus mutabilis leaves, is one of the component of Chinese medicine for treating cervical tuberculosis lymphadenitis[5]and flower for treating nasopharyngeal carcinoma[6]. Hibiscus esculentus extracts, used in cosmetics  improve skin wrinkles by inhibiting muscle contraction and removing oxygen free radicals[7].Above all it has been reported Hibiscus sabdariffa Linne  has anticancerous activity .Hibiscus polyphenol rich extract( HPE ) induces cell death of eight kinds of  carcinoma cell lines and it is most effective against human gastric carcinoma[8].Hibiscus anthocyanin, Delphinidin 3-sambubioside (Dp3-Sam) isolated from dried calcies of Hibiscus sabdariffa could induce a dose-dependent apoptosis in human leukemia cells (HL-60)[9].Another phenolic compound Hibiscus protocatechuic acid(PCA), isolated from the dried flower of Hibiscus sabdariffa has an antioxidant, antitumor suppressor activity and also effective against human promyelocytic leukemia HL-60 cells[10].In a US patent, publication number US2008113050inventor discovered a composition which is an anthocyanin extracts(Has) and effective for inhibiting the growth of leukemia cells without inhibiting the growth of normal leukemia. The plant tissue such as leaf, stem, flower or fruit used to extract HAs. So every partof Hibiscus sabdariffa has medicinal importance.

Plants commonly found around us have numerous medicinal properties and have been proved to be sources of many life saving drugs. Traditionally they have been used by our forefathers in our ancient medicinal systems but we need more effort to find out their uses in current scenario where we are struggling such as incurable diseases like AIDS and cancer.

 

References

(1)NS Parmar, MN Ghosh Indian Journal of Pharmacology, Year 1978, Volume 10, Issue 4 [p. 277-293])(antidiuretic effect)

(2 )Sachdewa A, Khemani LD. Effect of Hibiscus rosa sinensis Linn. ethanol flower extract on blood glucose and lipid profile in streptozotocin induced diabetes in rats. Journal of Ethnopharmacology.2003;89(1):61–66.

(3)Shivananda Nayak B, Sivachandra Raju S, Orette FA, Chalapathi Rao AV. Effects of Hibiscus rosa sinensis L (Malvaceae) on wound healing activity: a preclinical study in a Sprague Dawley rat. International Journal of Lower Extremity Wounds.2007;6(2):76–81.

 (4) Effects of Hibiscus rosa sinensis L (Malvaceae) on wound healing activity: a preclinical study in a Sprague Dawley rat.Shivananda Nayak B, Sivachandra Raju S, Orette FA, Chalapathi Rao AV

(5) Traditional Chinese medicine for treating cervical tuberculosis lymphadenitis.Publication number –CN-101721494(patent from espacenet)

[6] Chinese herbal prescription for treating nasopharyngeal carcinoma. Publication number-101757445 (patent from espacenet).

[7] Anti aging cosmetic composition. Publication number-US2010119628. (Patent from espacenet)

[8] Hibiscuspolyphenol-rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/FasL cascade pathwayHui-Hsuan Lin, Hui-Pei Huang, Chi-Chou Huang, Jing-Hsien Chen, 2005 Wiley-Liss, Inc(abstract) 

[9]Delphinidin 3-sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species-mediated mitochondrial pathway,De-Xing Hou,Xuhui Tong, Norihiko Terahara,Dong Luo,and Makoto Fujii,2005(abstract).

[10] Induction of apoptosis by Hibiscus protocatechuic acid in human leukemia cells via reduction of retinoblastoma (RB) phosphorylation and Bcl-2 expression. Tsui-Hwa Tseng, Ta-Wei Kao, Chia-Yih Chu, Fen-Pi Chou,Wei-Long Lin and Chau-Jong Wang.

Comments (0)